7. Blood types in humans are caused by a combination of two of three possible alleles I^A, I^B and i. The i allele is recessive and when an individual is homozygous for this allele, they have type O blood. Blood type A may be due to a homozygous condition (I^A, I^A ) or the heterozygous genotype (I^A , i). Blood type AB is caused by having a copy of both the I^A and I^B alleles. Rh factor is another marker on human red blood cells and is either positive (dominant R) or negative (recessive r). Give all possible genotypes for each blood type regarding I^A, I^B and i alleles.

TYPE BLOOD	GENOTYPE
A^+	I^A I^A R R I^A i R R I^A I^A R r I^A i R r
A^-	I^A I^A r r I^A i r r
B^+	I^B I^B R R I^B i R R I^B I^B R r I^B i R r
B^-	I^B I^B r r I^B i r r
AB^+	I^A I^BR R I^A I^BR r
AB^-	I^A I^Br r
O^+	i i R R i i R r
O^-	i i r r

A. A man that has blood type A negative, whose father was B positive and whose mother was AB positive, married a woman that was B positive. The woman’s mother was A negative and her father was AB positive. Give the genotypes of all the above mentioned individuals.

Man	I^A i r r
Man’s father	I^B i R r
Man’s mother	I^A I^BR r
Woman	I^B i R r
Woman’s mother	I^A i r r
Woman’s father	I^A I^BR R or I^A I^BR r

B. Give the genotypes and phenotypes of the possible offspring from this marriage.

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